2014年職稱英語(衛(wèi)生類)教材閱讀判斷文章及譯文15
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衛(wèi)生類-閱讀判斷
Beyond the Pap
Scientists have known for some time that virtually all cases of cervical cancer are triggered by a family of viruses called human papillomavirus, or HPV. Most women who become ineffected with HPV are able to shake off the virus and suffer no apparent long-term consequences to their health. But a few women develop a persistent infection that can, for reasons that are not entirely clear, eventually lead to cancerous changes in the cervix.
Now researchers at the Digene Corp of Beltsville, Maryland, have developed a test that detects an active HPV infection by looking for its genetic byproducts in the vagina. The HPV test was better than the standard Pap test at finding cervical cancer at any stage, according to two studies published this month in the Journal of the American Medical Association. So far, so good. Unfortunately, the test's false-positive rate―how often it indicated that there was a problem when none existed was almost twice as high as that for the Pap smear. In these cases, a biopsy of the woman’s cervix showed no sign of disease.
And that’s the crux of the problem. How many women should undergo what is, when it comes right down to it, unnecessary treatment to find a few more cases of cervical cancer? Shouldn’t health officials focus instead on making sure that more women undergo regular Pap-smear examinations? After all, Pap smears, though far from perfect, have helped dramatically lower the death toll from cervical cancer taking it from the No. 1 cause of death due to cancer in American women to the 10th.
Complicating matters is the fact that HPV is a very common infection. In some parts of the U.S. as many as half of all women under age 35 have an active case. Yet 99 out of 100 women who are HPV-positive will never get cervical cancer, estimates Dr. Joanna Cain, vice president of the American College of Obstetricians and Gynecologists. “If those 99 women live their lives as if they’re going to develop cancer”, she says, “we’re not necessarily doing them any good.”
At present, the HPV test is approved in the U. S. only to help resolve ambiguous results from a Pap-Smear test. Many gynecologists believe that HPV will eventually replace the pap. But they’re not willing to abandon it without a lot more detailed information and neither should you.
詞匯:
cervical 頸的;子宮頸的 trigger 發(fā)動(dòng),引起;促使
papillomavirus 乳頭狀瘤病毒 cancerous生癌的;患癌的;像癌的
cervix 器官的頸部 byproduct 附帶產(chǎn)生的結(jié)果;副產(chǎn)品
vagina 陰道 Pap smear,Pap test 尼科拉烏試驗(yàn),巴氏試驗(yàn)
smear(顯微鏡的)涂片;污跡,污斑;誹謗,詆毀
biopsy 活組織檢查;(為檢查和診斷而作的)活組織切除
obstetrician 產(chǎn)科醫(yī)師 gynecologist 婦科學(xué)家
ambiguous 含糊不清的;不明確的;難以理解(或區(qū)分)的
注釋:
1.Scientists have known for some time that virtually all cases of cervical cancer are triggered by a family of viruses called human papillomavirus, or HPV.一段時(shí)間以來,科學(xué)家們已經(jīng)知道幾乎所有子宮頸癌的病例都是由一組人類乳頭狀瘤病毒或HPV印發(fā)的。
2.Unfortunately, the test's false-positive rate―how often it indicated that there was a problem when none existed was almost twice as high as that for the Pap smear. 不幸的是,該檢驗(yàn)的假陽性率,即其顯示有問題而實(shí)際上并無問題的概率,幾乎是巴氏涂片假陽性率的兩倍。
3.How many women should undergo what is, when it comes right down to it, unnecessary treatment to find a few more cases of cervical cancer? 只是為了再多發(fā)現(xiàn)幾例子宮頸癌病例,多少婦女應(yīng)該接受那種說到底并不必要的治療呢?
練習(xí):
1. The cause of cervical cancer was discovered by American scientists some time ago.
A. Right B. Wrong C. Not mentioned
2. Only a few cases of HPV infection will lead to cancerous changes in the cervix.
A. Right B. Wrong C. Not mentioned
3. The HPV test was better than the standard Pap test in every aspect.
A. Right B. Wrong C. Not mentioned
4. Pap smears have contributed to the promotion of health of many women.
A. Right B. Wrong C. Not mentioned
5. Cervical cancer used to be the No. 1 killer cancer to women in America.
A. Right B. Wrong C. Not mentioned
6. Dr. Cain is against alarming the majority of women who, though HPV-positive, are unlikely to develop cervical cancer.
A. Right B. Wrong C. Not mentioned
7. The author also believes that HPV will eventually replace the Pap.
A. Right B. Wrong C. Not mentioned
答案與題解:
1.C 文章一開頭指出,一段時(shí)間以來,科學(xué)家們已經(jīng) 知道幾乎所有子宮頸癌的病例都是由一組人類乳頭狀瘤病毒或HPV印發(fā)的,但文章并未提及子宮頸癌的原因是否是美國科學(xué)家所發(fā)現(xiàn)的。故選項(xiàng)C為答案。
2.A 文章第一段指出,大多數(shù)感染人類乳頭狀瘤病毒的婦女都能好起來,該病毒不會(huì)對(duì)她們的健康造成什么明顯的長期影響,但是也有一些婦女會(huì)持續(xù)感染這種病毒后發(fā)生子宮頸癌變。故選項(xiàng)A為答案。
3.B 文章第二段指出,最新發(fā)表的亮相研究成果表明,這種人類乳頭狀瘤病毒檢測(cè)方法在發(fā)現(xiàn)處于任何階段的子宮頸癌方面優(yōu)于標(biāo)準(zhǔn)的巴氏試驗(yàn),但不幸的是,這種檢驗(yàn)的假陽性率,卻幾乎是巴氏涂片假陽性率的兩倍。故選項(xiàng)B為答案。
4.A 文章第三段指出,巴氏試驗(yàn)雖然遠(yuǎn)非完善,但卻使因子宮頸癌而喪生的人數(shù)大大降低,因此可以說這種試驗(yàn)隊(duì)增進(jìn)許多婦女的健康做出了貢獻(xiàn)。故選項(xiàng)A為答案。
5.A 文章第三段末尾提到,子宮頸癌過去曾是美國婦女所面臨的頭號(hào)癌癥殺手。故選項(xiàng)A為答案。
6.A 文章第四段提到,凱恩博士認(rèn)為,99%人類乳頭狀瘤病毒陽性的婦女都不會(huì)患子宮頸癌,因此如果醫(yī)務(wù)工作者使得這些人惶惶不安,擔(dān)心總有一日會(huì)患子宮頸癌,這與其說是在幫她們的忙還不如說是在害她們。故選項(xiàng)A為答案。
7.C 在文章的最后一段,作者說許多婦科學(xué)家相信,人類乳頭狀瘤病毒試驗(yàn)遲早會(huì)取代巴氏試驗(yàn),但作者 并未標(biāo)明自己的觀點(diǎn)。故選項(xiàng)C為答案。
譯文:巴氏試驗(yàn)之外
一段時(shí)間以來,科學(xué)家們已經(jīng)知道幾乎所有子宮頸癌的病例都是由一組人類乳頭狀瘤病毒或HPV引發(fā)的。大部分感染上HPV的女人都可以擺脫這種病毒,對(duì)她們的健康 不再有明顯的長期后果。但有一些女人會(huì)引發(fā)持續(xù)感染,因某些不太清楚的原因會(huì)最終導(dǎo)致子宮頸癌變。
現(xiàn)在馬里蘭州貝爾茲威爾的迪吉納公司的研究員開發(fā)了一種通過尋找陰道內(nèi)的HPV基因副產(chǎn)品而檢測(cè)陽性HPV感染 的試驗(yàn)。據(jù)這個(gè)月《美國醫(yī)學(xué)協(xié)會(huì)雜志》上的兩項(xiàng)研究表明,HPV試驗(yàn)在發(fā)現(xiàn)處于各個(gè)階段的子宮頸癌的效果方面比巴氏試驗(yàn)更好。到目前為止,一切順利。 不幸的是,該檢驗(yàn)的假陽性率,即其顯示有問題而實(shí)際上并無問題的概率,幾乎是巴氏涂片假陽性率的兩倍。這些情況下,女性子宮頸癌活組織檢查顯示沒有疾病。
這是這個(gè)問題 的癥結(jié)所在。只是為了再多發(fā)現(xiàn)幾例子宮頸癌病例,多少婦女應(yīng)該接受那種說到底并不必要的治療呢?難倒衛(wèi)生官員們不應(yīng)該把目標(biāo)放在確保更多的婦女接受巴氏試驗(yàn)上嗎?畢竟,雖然巴氏涂片遠(yuǎn)非晚上,卻在很大程度上降低了子宮頸癌的死亡率――把它從導(dǎo)致美國婦女死亡的頭號(hào)癌癥變?yōu)榈谑弧?/P>
復(fù)雜的是HPV是一種非常常見的感染。在美國的某些地方,有一般的35歲以下婦女呈HPV陽性。美國產(chǎn)科醫(yī)師和婦科學(xué)家大學(xué)的副校長Joanna Cain 博士估計(jì)100個(gè)HPV呈陽性的婦女中,99個(gè)不會(huì)患子宮頸癌。她說:”如果那99個(gè)人像她們要患癌一樣生活,我們根本沒給她們帶來任何好處。
現(xiàn)在,HPV在美國被批準(zhǔn)輔助解決巴氏涂片測(cè)驗(yàn)的模糊結(jié)果。許多付科學(xué)家相信最終HPV試驗(yàn)將代替巴氏試驗(yàn)。但是沒有許多詳細(xì)信息的情況下他們不愿意放棄巴氏試驗(yàn)――你也不應(yīng)該。
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